Adefovir nephrotoxicity in a renal allograft recipient
نویسندگان
چکیده
منابع مشابه
Adefovir nephrotoxicity in a renal allograft recipient
Adefovir dipivoxil, an oral prodrug of adefovir, is used in the treatment of lamivudine-resistant hepatitis B virus (HBV) infection. Nephrotoxicity manifesting as proximal renal tubular dysfunction and acute tubular necrosis (ATN) were commonly reported in the past, when higher doses were used for the treatment of human immunodeficiency virus infection. However, nephrotoxicity is rare at lower ...
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A 65-year-old female received a renal transplantation 3 years ago, and her maintenance immunosuppressive regimen included prednisolone 5 mg once daily (0.1 mg/kg/ day), mycophenolate mofetil 1 g twice daily and cyclosporin 125 mg twice daily (5 mg/kg/day) with average trough serum levels of cyclosporine between 200 and 300 ng/mL since 3 months after renal transplantation. Her first episode of g...
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BACKGROUND The introduction of the calcineurin inhibitors (CI) cyclosporine and tacrolimus into immunosuppressive protocols initiated a new era in organ transplantation with excellent short-term graft survival. Nevertheless, the chronic nephrotoxicity of these drugs represents a significant adverse factor limiting their long-term use. Patients treated with a CI can be at risk for developing ren...
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Extra-pulmonary tuberculosis (TB) is more common in renal allograft recipients and may present with dissemination or an atypical features. We report a renal allograft recipient with intestinal TB presenting 3 years after transplantation with persistent fever, weight loss, diarrhea, abdominal pain and mass in the abdomen with intestinal obstruction. He was diagnosed to be having an ileocolic int...
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cyclosporin may not greatly increase the toxicity ofaggressive chemotherapy used in the treatment of haematological malignancies. Sonneveld and Nooter reported a patient with resistent AML to whom they administered cyclosporin without any excessive toxicity, although their patient had profound marrow hypoplasia for three weeks.9 Septic shock is a well recognised problem in severely neutropenic ...
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ژورنال
عنوان ژورنال: Indian Journal of Nephrology
سال: 2015
ISSN: 0971-4065
DOI: 10.4103/0971-4065.144423